Effects of threshold inspiratory muscle training on respiratory function, motor function and quality of life for patients with chronic obstructive pulmonary disease: a meta-analysis
10.3969/j.issn.1006-9771.2022.09.004
- VernacularTitle:阈值负荷吸气肌训练对慢性阻塞性肺疾病患者呼吸功能、运动功能及生活质量影响的Meta分析
- Author:
Juan PENG
1
;
Jieping WANG
1
;
Wei HUANG
2
;
Bishuang FAN
1
;
Jihua YU
1
;
Jin ZENG
1
;
Liheng HUANG
1
;
Lijuan AN
1
;
Fangyuan XU
1
Author Information
1. Department of Rehabilitaion, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
2. Department of Endocrinology and Metabolism, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
- Publication Type:Journal Article
- Keywords:
threshold inspiratory muscle training;
chronic obstructive pulmonary disease;
randomized controlled trial;
meta-analysis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2022;28(9):1022-1031
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo systematically evaluate the effects of threshold inspiratory muscle training (TIMT) on respiratory function, motor function and quality of life in patients with chronic obstructive pulmonary disease (COPD). MethodsRandomized controlled trials (RCT) about the effects of TIMT on dyspnea, quality of life, motor function and inspiratory muscle strength for COPD patients were retrieved from PubMed, EBSCO, Web of Science, Ovid, Cochrane Library, SinoMed, CNKI, VIP, since establishment to September, 2020. Two researchers independently screened literatures, extracted data and evaluated the methodological quality. A meta-analysis was performed using RevMan 5.3. ResultsA total of 30 RCTs involving 2 060 patients were included. TIMT could obviously improve the maximum inspiratory pressure (MD = 10.68, 95%CI 7.43 to 13.92, P < 0.001), optimize the results of 6-minute Walking Test (MD = 24.62, 95%CI 9.09 to 40.15, P = 0.002), the St George's Respiratory Questionnaire (MD = -3.08, 95%CI -5.84 to -0.33, P = 0.03), the modified Medical Research Council Dyspnea Scale (MD = -0.30, 95%CI -0.52 to -0.07, P = 0.01) and Borg score (MD = -0.84, 95%CI -1.24 to -0.44, P < 0.001). TIMT could also improve the forced expiratory volume in one second (MD = 0.11, 95%CI 0.04 to 0.19, P = 0.003) and the forced expiratory volume in one second in predicted (MD = 3.72, 95%CI 2.62 to 4.82, P < 0.001). There was no significant difference in the COPD Assessment Test (MD = -1.14, 95%CI -2.32 to 0.03, P = 0.06) or forced vital capacity (MD = 0.07, 95%CI -0.12 to 0.25, P = 0.49). ConclusionTIMT can improve the inspiratory muscle strength, alleviate the symptoms of dyspnea, and improve the lung function and the quality of life for COPD patients.
