Current management status of hereditary colorectal cancer.
10.3760/cma.j.cn441530-20211111-00457
- VernacularTitle:遗传性结直肠癌的诊治现状
- Author:
Gan Bin LI
1
;
Zhen Jun WANG
1
;
Jia Gang HAN
1
Author Information
1. Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms, hereditary;
Familial adenomatous polyposis;
Lynch syndrome;
Surgical treatment
- MeSH:
Adenomatous Polyposis Coli/surgery*;
Anastomosis, Surgical/methods*;
Colectomy;
Colorectal Neoplasms, Hereditary Nonpolyposis/surgery*;
Humans;
Proctocolectomy, Restorative/methods*;
Retrospective Studies
- From:
Chinese Journal of Gastrointestinal Surgery
2022;25(6):546-551
- CountryChina
- Language:Chinese
-
Abstract:
Hereditary colorectal cancer accounts for approximately 5% of all colorectal cancer cases, mainly including familial adenomatous polyposis and Lynch syndrome. Total proctocolectomy plus ileal pouch-anal anastomosis and total colectomy plus ileorectal anastomosis are two major procedures for familial adenomatous polyposis, however, the exact impact of these two procedures on surgical efficacy, oncologic efficacy as well as functional results still remains uncertain. Segmental colectomy and total colectomy are two major procedures for Lynch syndrome, each of them both has advantages and disadvantages, and there still lacks a consensus about the optimal strategy because of the nature of retrospective study with a relatively insufficient evidence support. As a result, we would make a review about the current surgical treatment status and future perspectives of hereditary colorectal cancer.
