Primary Cutaneous CD30-negative Large T-cell Lymphoma.
- Author:
Eun Young CHUN
1
;
Sung Won WHANG
;
You Chan KIM
;
Soo Chan KIM
Author Information
1. Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea. kimsc@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Primary cutaneous CD30-negative large T-cell lymphoma
- MeSH:
Dermis;
Female;
Humans;
Leg;
Lymphocytes;
Lymphoma, T-Cell*;
Lymphoma, T-Cell, Cutaneous;
Middle Aged;
Mycosis Fungoides;
Subcutaneous Fat;
T-Lymphocytes*;
Ulcer
- From:Korean Journal of Dermatology
2002;40(8):942-945
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary cutaneous CD30-negative large T-cell lymphoma without prior or concurrent mycosis fungoides represents a distinct group of cutaneous T-cell lymphoma with an aggressive clinical behavior. Primary cutaneous CD30-negative large T-cell lymphoma is a rare disorder which represents only about 5% of primary cutaneous T-cell lymphoma. A 51-year-old woman presented with a rapid growing, ulcerative plaque on the right lower leg of 2 years duration. Histologically, it showed diffuse infiltrates with a predominance of medium-sized to large pleomorphic lymphocytes in the dermis and subcutaneous fat layers, which stained positively with CD3 and negatively with CD20, CD30, CD56 on immunohistochemical staining. There was no evidence of extracutaneous metastsis.
