A challenge for colorectal surgeons: pathogenesis, progression and management of the secondary tumors of the ovary.
10.3760/cma.j.issn.441530-20210506-00192
- Author:
Jing Yi SHI
1
;
Yong YANG
1
;
An HUANG
1
;
Jing Xuan XU
1
;
Yu CHENG
1
;
Yu Kun LI
1
;
Jin GU
2
Author Information
1. Department of Gastrointestinal Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
2. Department of Gastrointestinal Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing 100144, China Peking-Tsinghua Center for Life Science, Beijing 100142, China.
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Krukenberg tumor;
Metastasis;
Secondary tumors of the ovary (STO)
- MeSH:
Colorectal Neoplasms/therapy*;
Female;
Humans;
Krukenberg Tumor;
Ovarian Neoplasms/surgery*;
Prognosis;
Surgeons
- From:
Chinese Journal of Gastrointestinal Surgery
2021;24(6):550-556
- CountryChina
- Language:Chinese
-
Abstract:
A common clinical problem encountered by colorectal surgeons is the secondary tumors of the ovary (STO), particularly in young female patients. Most STO are from the digestive tract, and the known possible metastatic mechanisms include lymphatic, hematogenous, and intraperitoneal spreading. The molecular and histopathological characteristics of STO from different sites are diverse. It is particularly important to correctly identify the origin and feature of STO, which should be clarified by combining medical history, histopathology, immunohistochemistry, molecular biology, imaging and other means. The prognosis of patients with STO is poor in general. Comprehensive therapies based on surgical resection can benefit some patients. There is no specific treatment for STO at present, but not giving up easily on these patients is the right choice that every surgeon should understand.
