Progress in gastric cancer with positive peritoneal cytology.
10.3760/cma.j.cn.441530-20200305-00122
- Author:
Bai Long LI
1
;
Ru Lin MIAO
1
;
Zi Yu LI
1
Author Information
1. Center of Gastrointestinal Tumors, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
- Publication Type:Journal Article
- Keywords:
Detection;
Pathogenesis;
Positive peritoneal cytology;
Stomach neoplasms;
Therapy
- MeSH:
China;
Gastrectomy;
Humans;
Neoplasm Staging;
Peritoneal Lavage;
Peritoneal Neoplasms/diagnosis*;
Prognosis;
Retrospective Studies;
Stomach Neoplasms/surgery*
- From:
Chinese Journal of Gastrointestinal Surgery
2021;24(5):458-462
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer with positive peritoneal cytology is a hotspot in the study of gastric cancer, and its prognosis is poor. Intraperitoneal free cancer cells may be associated with cancer cells migration, invasion and metastasis. Tumor T stage, peritoneal metastasis, lymph node metastasis, low histological differentiation, linitis plastica, adenocarcinoma of esophagogastric junction, and operation are the clinicopathological risk factors of gastric cancer with positive peritoneal cytology. Currently, the acquisition of free cancer cells is mainly through diagnostic laparoscopy combined with peritoneal lavage, and cytopathological examination is gold standard for diagnosis. Its treatment strategies are not in consensus, including preoperative chemotherapy combined with radical resection, postoperative chemotherapy and peritoneal local treatment, which can prolong the survival of patients. At present, postoperative chemotherapy is often used in China, and the best treatment strategies remain to be further studied.
