Progress in Clinical Research of Amide Proton Transfer Imaging.
10.3969/j.issn.1671-7104.2020.02.018
- Author:
Xuan JIA
1
;
Can LAI
1
;
Xiaohui MA
1
Author Information
1. Department of Radiology, Children's Hospital Affiliated to Zhejiang University School of Medicine, Hangzhou, 310052.
- Publication Type:Review
- Keywords:
amide proton transfer;
chemical exchange saturation transfer;
magnetic rresonance imaging
- MeSH:
Abdomen/pathology*;
Amides;
Child;
Humans;
Magnetic Resonance Imaging;
Neoplasms/diagnostic imaging*;
Protons
- From:
Chinese Journal of Medical Instrumentation
2020;44(2):185-188
- CountryChina
- Language:Chinese
-
Abstract:
As a new type of magnetic resonance imaging method, amide proton transfer (APT) imaging can detect the chemical exchange characteristics of free proprotein, peptide amide proton and water proton by water signal changes, reflecting the changes of protein and pH in tissues. In recent years, clinical research on brain tumors, multiple sclerosis, hepatic encephalopathy and cervical cancer have been carried out. It is a radiation-free and non-invasive new magnetic resonance molecular imaging technology. This study briefly reviews the principle of APT technology and its clinical application, and prospects its application prospects in children's abdominal tumors.
