Research advances in the early predictive factors for non-neoplastic portal vein thrombosis in liver cirrhosis
10.3969/j.issn.1001-5256.2022.09.039
- VernacularTitle:肝硬化患者非肿瘤性门静脉血栓形成的早期预测因子
- Author:
Zunlan ZHOU
1
,
2
;
Lina YANG
1
;
Qingqing LI
1
;
Hong WANG
1
Author Information
1. Department of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, China
2. Department of Gastroenterology, Guizhou Aerospace Hospital, Zunyi, Guizhou 563000, China
- Publication Type:Reviews
- Keywords:
Liver Cirrhosis;
Venous Thrombosis;
Risk Factors
- From:
Journal of Clinical Hepatology
2022;38(9):2150-2154
- CountryChina
- Language:Chinese
-
Abstract:
Portal vein thrombosis (PVT) is one of the common complications in patients with decompensated liver cirrhosis, including non-neoplastic PVT and portal vein tumor thrombus after the onset of primary liver cancer. It can lead to the deterioration of liver function, aggravate the portal hypertension-related adverse events including esophagogastric variceal bleeding, reduce the survival rate of patients after liver transplantation, and even threaten the life of patients in severe cases. Therefore, it is of great clinical significance to further explore the risk factors and early predictive factors for PVT. This article elaborates on the recent advances in the early predictive factors for non-neoplastic PVT in liver cirrhosis from the aspects of the three elements of thrombosis, the severity of liver injury, and the endoscopic treatment of esophagogastric varices. The analysis of related research shows that some early predictive factors are clearly associated with the formation of PVT, which provides help for the early identification of PVT; however, specific predictive values may be unclear or have certain differences, which needs to be confirmed by multicenter prospective studies.
