Prediction of perioperative hyperkalemia in dialysis patients with secondary hyperparathyroidism.
10.3760/cma.j.cn115330-20201216-00924
- VernacularTitle:继发性甲状旁腺功能亢进围手术期高钾血症的预测分析
- Author:
Wei Jian OU
1
;
Jing KANG
1
;
Shuang Xin LIU
2
;
Si Jia LI
2
;
Shao Hua CHEN
1
;
Si Yi ZHANG
1
;
Ping Jiang GE
1
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Guangzhou 510030, China.
2. Department of Nephrology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Guangzhou 510030, China.
- Publication Type:Journal Article
- MeSH:
Calcium;
Female;
Humans;
Hyperkalemia/etiology*;
Hyperparathyroidism, Secondary/surgery*;
Male;
Parathyroid Hormone;
Parathyroidectomy;
Renal Dialysis;
Retrospective Studies
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2021;56(8):854-857
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the influencing factors for serum potassium >4.4 mmol/L in the morning of parathyroidectomy in hemodialysis patients with secondary hyperparathyroidism (SHPT). Methods: The clinical data of 72 patients with SHPT who received regular hemodialysis and underwent parathyroidectomy in Guangdong Provincial People's Hospital from January 2012 to December 2018 were analyzed retrospectively. There were 37 males and 35 females, aged from 25 to 69 years, and the dialysis timespan was from 0.5 to 11 years. The levels of parathyroid hormone, serum potassium and serum calcium before hemodialysis were examined one day before operation, and hemodialysis time and dewatering volume after hemodialysis without heparin were recorded, and also the level of serum potassium in the morning of parathyroidectomy was detected. The occurrences of hyperkalemia during and after operation were studied. The factors related to hyperkalemia in the morning of parathyroidectomy were evaluated by Pearson or Spearman correlation analysis, and the cut-off values of risk factors were calculated by receiver operating characteristic (ROC) curve. Results: Serum potassium >4.4 mmol/L in the morning of parathyroidectomy existed in 23 of 72 patients. Correlation analysis showed that serum potassium one day before operation ((4.93±0.56)mmol/L, r=0.656, P<0.001) and dehydration volume ((2.37±0.75)L, r=0.261, P=0.027) were positively correlated with serum potassium in the morning of parathyroidectomy((4.16±0.54)mmol/L). Serum potassium before hemodialysis one day before operation was a main predictor for serum potassium in the morning of parathyroidectomy (AUC=0.791, P<0.001). The cut-off value of serum potassium before hemodialysis one day before operation was 5.0 mmol/L. Conclusion: Serum potassium before hemodialysis one day before operation in patients with SHPT can predict serum potassium in the morning of parathyroidectomy, offering imformation for the safety of operation.
