Substitutes for Endangered Animal Medicinal Materials: A Review
10.13422/j.cnki.syfjx.20220247
- VernacularTitle:濒危动物药材替代品的研究进展
- Author:
Xun YE
1
;
Xiaochuan WU
1
;
Lin HE
1
;
Zibo LIU
1
;
Xue SUN
1
;
Haozhong WANG
1
;
Chongyang SHEN
1
;
Chunjie WU
1
Author Information
1. School of Pharmacy,School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China
- Publication Type:Review
- Keywords:
endangered animal medicinal materials;
Chinese materia medica;
alternatives;
solutions;
origin;
artificial synthesis;
breeding
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2022;28(20):226-231
- CountryChina
- Language:Chinese
-
Abstract:
Endangered animal medicine is an important part of traditional Chinese medicine, which is distinctive in the treatment of diseases. At present, the rare and endangered medicinal materials such as tiger bone, rhinoceros horn, pangolin, antelope horn, bear bile are listed as national key protected animals, so their clinical application is limited, the current solution is mainly based on the ideas and methods of similar pharmacological effects, close genetic relationships, artificial breeding, and artificial synthesis to find and develop alternatives for endangered animal medicinal materials. Although artificially cultured bear bile and musk, and artificially synthesized tiger bone, bezoar and musk can solve the shortage of endangered animal medicines to a certain extent, there are still some problems such as difficult breakthroughs in breeding technology and incomplete recognition in the substitute industry. According to this, based on summarizing the existing substitutes for endangered animal medicines, our group proposed the concept of homology, homogeneity and equivalent of substitutes, and constructed a new idea to develop and evaluate substitutes by combining frontier biotechnology with multi-omics detection, so as to provide some support for protecting rare and endangered animals and solving the shortage of endangered animal medicines.