Application of Neuroform EZ stent in the treatment of severe intracranial arterial stenosis with complex symptomatic.
- Author:
Zi Chang JIA
1
;
Huan Ju BIAN
2
;
Xuan LI
1
;
Jing Yuan LUAN
1
;
Chang Ming WANG
1
;
Qi Jia LIU
1
;
Jin Tao HAN
1
Author Information
1. Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
2. Department of Neurology, Guanxian People's Hospital, Liaocheng 252500, Shandong, China.
- Publication Type:Journal Article
- MeSH:
Cerebral Angiography;
Constriction, Pathologic;
Follow-Up Studies;
Humans;
Retrospective Studies;
Stents;
Treatment Outcome
- From:
Journal of Peking University(Health Sciences)
2019;51(5):835-839
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To assess the safety and efficacy of Neuroform EZ stent used in treatment of symptomatic complex severe intracranial atherosclerotic stenosis (ICAS).
METHODS:Clinical data of 18 patients with symptomatic complex severe ICAS undergoing Neuroform EZ stent angioplasty from January 2016 to December 2017 were retrospectively analyzed. All the lesions of the patients in this group were considered as complex ICAS, i.e. with severe tortuous access, long (>10 mm) or occlusive or bifurcation lesions, with concurrent aneurysms near the stenotic lesion. The primary outcome was defined as any stroke (including ischemic or hemorrhagic) or deaths from any cause after stenting procedure within 30 days. The secondary outcome was defined as successful revascularization and occurrence of >50% in-stent restenosis during the follow-up period.
RESULTS:All the 18 patients achieved technical success (100%) and mean stenosis rate was reduced from 85%±7% to 18%±6%. Of the 18 patients included, the 30-day stroke or death was 5.6% (1/18), which presented as basal ganglia region infarction in a patient with tandem lesions on the left vertebral artery. There was no hemorrhagic and death complications that occurred in the patients of this group. One concurrent aneurysm was embolized with micro coil (stent assisted) by stages after 1 month. In this group 12 patients were followed up with digital subtraction angiography (DSA) after hospital discharge. The follow-up period ranged from 8 months to 26 months [mean: (16±8) months]．During the follow-up period 2 patients in the 12 patients (2/12, 16.7%) developed in-stent restenosis (ISR) confirmed by DSA, and one of them was symptomatic restenosis and restored unobstructed blood flow after balloon angioplasty.
CONCLUSION:Neuroform EZ stent for the treatment of highly screened symptomatic complex severe ICAS is safe and effective. It has its advantages over traditional stent.
