Advance in Research of Biomarkers of Spinal Cord Injury (review)
10.3969/j.issn.1006-9771.2015.09.013
- VernacularTitle:脊髓损伤生物标记物的研究进展
- Author:
Yuming WANG
;
Li TANG
;
Degang YANG
;
Zhimin ZHU
- Publication Type:Journal Article
- Keywords:
spinal cord injury, biomarker, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2015;21(9):1045-1048
- CountryChina
- Language:Chinese
-
Abstract:
Various functional proteins are differently expressed in each pathologic stage after spinal cord injury, representing injury and the pathological change of repair. Ideal biomarker is helpful to evaluate complicated biological reactions of spinal cord injury and predict prognosis. As specific serum markers of central nerve injury, neuron-specific enolase (NSE) and astrocyte primary calcium binding protein S-100β had been studied preliminarily, but the specificity and sensitivity need more research. Future efforts still need to develop ideal biomarkers to predict functional outcome.
