Role of traditional Chinese medicine in treatment of chronic hepatitis B by nucleos(t)ide analogues
10.3969/j.issn.1001-5256.2022.08.033
- VernacularTitle:中医药在核苷(酸)类似物治疗慢性乙型肝炎中的作用
- Author:
Hanxiao WANG
1
;
Xinju CHEN
2
;
Qing ZHAO
2
;
Wenxia ZHAO
2
Author Information
1. The First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450000, China
2. Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China
- Publication Type:Reviews
- Keywords:
Hepatitis B, Chronic;
Liver Cirrhosis;
Carcinoma, Hepatocellular;
Nucleotides;
Drugs, Chinese Herbal
- From:
Journal of Clinical Hepatology
2022;38(8):1886-1891
- CountryChina
- Language:Chinese
-
Abstract:
Nucleos(t)ide analogues (NUC) can inhibit the replication of hepatitis B virus (HBV) and effectively treat chronic hepatitis B (CHB), but they cannot completely eradicate HBV and cannot prevent the progression to hepatitis B cirrhosis and liver cancer in the context of a low viral load. In recent years, traditional Chinese medicine has been widely used in the treatment of CHB. This article elaborates on the application and mechanism of traditional Chinese medicine in inhibiting HBV replication, reducing the content of HBeAg, and delaying the progression to hepatitis B cirrhosis, and it is proposed that traditional Chinese medicine can improve the therapeutic effect of NUC in the treatment of CHB.
