Exploration and practice of information-based pharmaceutical care pathway of anticoagulant therapy in patients with atrial fibrillation
- VernacularTitle:房颤患者抗凝治疗信息化药学监护路径的探索与实践
- Author:
Jing LI
1
;
Xiao ZHOU
1
;
Huizhu SONG
1
;
Hongyan MA
1
;
Ying GONG
1
;
Zhengyue QIAN
1
Author Information
1. Dept. of Pharmacy，the Affiliated Wuxi People’s Hospital of Nanjing M edical University，Jiangsu Wuxi 214023，China
- Publication Type:Journal Article
- Keywords:
atrial fibrillation;
anticoagulant therapy;
informatization;
pharmaceutical care pathway
- From:
China Pharmacy
2022;33(17):2162-2166
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIV E To develop the infor mation-based pharmaceutical care pathway of anticoagulant therapy in patients with atrial fibrillation and improve the efficacy and safety of treatment for them. METHODS The“anticoagulant pharmaceutical care”module was developed on the basis of medical intelligent and decision system. Patients with atrial fibrillation were taken pharmaceutical care in the whole anticoagulant treatment by evaluating the thromboembolism and bleeding risks ，pre-reviewing antithrombotic prescriptions ，monitoring efficacy and drug interactions ，and warning adverse reactions. RESULTS A total of 1 228 patients receiving anticoagulant therapy were enrolled. It was found after analysis of their doctor ’s orders that 9.27％ of the patients adjusted the improper antithrombotic therapies ，3.99％ modulated treatments according to the effects of potential drug interactions or the risk of adverse reactions ，and 70.29％ of the wrong prescriptions were intervened successfully. After the information-based pharmaceutical care ，the anticoagulation treatment rate increased from 88.73％ to 97.40％，the rate of patients ’achievements to warfarin’s international normalized ratio in hospital increased from 38.64％ to 66.67％，and the incidence of serious bleeding events decreased from 2.94％ to 0.37％ （P＜0.05）. CONCLUSIONS The information-based pharmaceutical care path of anticoagulant therapy achieved comprehensive ，efficient and accurate management of patients with atrial fibrillation ，and improved the rationality ，effectiveness and safety of anticoagulant therapy.
