Risk factor distribution features and trends of young adults with first acute coronary syndrome.
10.3760/cma.j.cn112148-20200417-00324
- Author:
Hong Xia YANG
1
;
Hui Juan ZUO
2
;
Shu Jie JIA
1
;
Pu Cong YE
3
;
Hao Ran XING
3
;
Xin ZHAO
3
;
Xue Yao YANG
3
;
Wen Yi ZHANG
3
;
Xian Tao SONG
3
Author Information
1. Department of Comprehensive Medical, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
2. Beijing Anzhen Hospital, Capital Medical University, Department of Community Health Research, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.
3. Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
- Publication Type:Journal Article
- From:
Chinese Journal of Cardiology
2021;49(3):242-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the characteristics and trends during the last 11 years of risk factors of young adults with first acute coronary syndrome (ACS). Methods: It was a cross-sectional study. We included young adults (18 to 44 years old) hospitalized for acute coronary syndrome in Beijing Anzhen Hospital for a first time from January 2007 to December 2017. Acute coronary syndromes include ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina (UA). The general information, medical history and laboratory test were recorded. Risk factors of ACS were smoking, dyslipidemia, overweight/obesity, hypertension and diabetes. Results: Data from 7 106 patients were analyzed, mean age was (39.8±4.2) years old and 6 593(92.8%)were men, including 2 254 (31.7%) STEMI, 704 (9.9%) NSTEMI and 4 148 (58.4%) UA. Most patients were male (6 593(92.8%)). Dyslipidemia (85.8%(6 094/7 106)), overweight/obesity (82.3%(5 850/7 106)), and smoking (63.9%(4 545/7 106)) were most prevalent. 98.3% (6 885/7 106) patients had at least 1 risk factor. The prevalence of hypertension, diabetes and overweight/obesity increased from 2007 to 2017. Rates of hypertension increased from 37.1%(111/299) to 48.1%(498/1 035) (Ptrend<0.01), diabetes from 12.0%(36/299) to 19.4%(201/1 035) (Ptrend<0.01), overweight/obesity from 74.2%(222/299) to 83.9%(868/1 035) (Ptrend<0.05), respectively. Conclusions: Dyslipidemia, overweight/obesity and smoking are most prevalent risk factors in young adults with a first ACS and most patients have at least 1 risk factor for ACS. Rates of hypertension, diabetes and overweight/obesity progressively increases over time in this patient cohort.
