Comparison of heart failure and COVID-19 in chest CT features and clinical characteristics.
10.3760/cma.j.cn112148-20200218-00093
- Author:
Zhao Wei ZHU
1
;
Jian Jun TANG
1
;
Xiang Ping CHAI
2
;
Zhen Fei FANG
1
;
Qi Ming LIU
1
;
Xin Qun HU
1
;
Dan Yan XU
1
;
Liang TANG
1
;
Shi TAI
1
;
Yu Zhi WU
3
;
Sheng Hua ZHOU
1
Author Information
1. Department of Cardiology, Second Xiangya Hospital of Central South University, Changsha 410011, China.
2. Emergency Depratment, Second Xiangya Hospital of Central South University, Changsha 410011, China.
3. Department of Radiology,Second Xiangya Hospital of Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- Keywords:
COVID-19;
Heart failure;
Pulmonary computed tomography
- MeSH:
Betacoronavirus;
COVID-19;
Coronavirus Infections/diagnostic imaging*;
Heart Failure/etiology*;
Humans;
Pandemics;
Pneumonia, Viral/diagnostic imaging*;
Retrospective Studies;
SARS-CoV-2;
Tomography, X-Ray Computed
- From:
Chinese Journal of Cardiology
2020;48(6):467-471
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To identify the characteristics including clinical features and pulmonary computed tomography (CT) features of heart failure and COVID-19. Methods: This study was a retrospective study. A total of 7 patients with heart failure and 12 patients with COVID-19 in the Second Xiangya Hospital of Central South University between December 1, 2019 and February 15, 2020 were enrolled. The baseline clinical and imaging features of the two groups were statistically analyzed. Results: There was no significant difference in age and sex between the two groups(both P>0.05), but the incidence of epidemiological contact history, fever or respiratory symptoms in the COVID-19 group was significantly higher than that in the heart failure group (12/12 vs. 0, P<0.001; 12/12 vs. 4/7, P=0.013). While the proportion of cardiovascular diseases and impaired cardiac function was significantly less than that of the heart failure group(2/12 vs.7/7, P<0.001；0 vs.7/7, P<0.001). For imaging features, both groups had ground-glass opacity and thickening of interlobular septum, but the ratio of central and gradient distribution was higher in patients with heart failure than that in patients with COVID-19 (4/7 vs. 1/12, P=0.04). In heart failure group, the ratio of the expansion of pulmonary veins was also higher (3/7 vs. 0，P=0.013), and the lung lesions can be significantly improved after effective anti-heart failure treatment. Besides, there were more cases with rounded morphology in COVID-19 group（9/12 vs. 2/7, P=0.048）. Conclusions: More patients with COVID-19 have epidemiological history and fever or respiratory symptoms. There are significant differences in chest CT features, such as enlargement of pulmonary veins, lesions distribution and morphology between heart failure and COVID-19.
