Research advances on the pathogenesis and diagnosis of pyoderma gangrenosum.
10.3760/cma.j.cn501225-20220331-00117
- Author:
Lan YANG
1
;
Qing Wen YANG
2
;
Yan Jie FU
3
Author Information
1. The Second Clinical Medical College, Binzhou Medical University, Yantai 264003, China.
2. The Clinical Medical College, Weifang Medical University, Weifang 261053, China.
3. Department of Burns and Plastic Surgery, Linyi People's Hospital, Linyi 276002, China.
- Publication Type:Review
- MeSH:
Humans;
Pyoderma Gangrenosum/pathology*
- From:
Chinese Journal of Burns
2022;38(6):569-573
- CountryChina
- Language:Chinese
-
Abstract:
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis, closely associated with the immune system. Its pathogenesis is currently not clear. The lack of specificity in the clinical manifestations and histopathological changes of PG leads to a long clinical diagnosis cycle and even misdiagnosis, which is easy to delay treatment or promote the deterioration of ulcer wound. The diagnosis of this disease is still very difficult, which poses a great challenge to wound repair practitioners. This article reviews the research advances on the pathophysiology, clinical features, and diagnosis of PG in recent years, with the aim of providing reference for relevant clinical practitioners.
