Discussion on Pharmacopoeia Standard and Drug Site of Amomi Fructus Based on Quality Investigation of Commercial Samples
10.13422/j.cnki.syfjx.20211948
- VernacularTitle:基于市售样品质量考察的砂仁药典标准及用药部位探讨
- Author:
Jun ZHANG
1
;
Qi LU
1
;
Xiaofan ZHANG
2
;
Yanpeng DAI
1
;
Longhui ZU
1
;
Zhaoshuang ZHAN
3
;
Dianhua SHI
1
Author Information
1. Shandong Academy of Chinese Medicine，Jinan 250014，China
2. Neck-shoulder and Lumbocrural Pain Hospital of Shandong First Medical University，Jinan 250013，China
3. Shandong University of Traditional Chinese Medicine，Jinan 250355，China
- Publication Type:Journal Article
- Keywords:
Amomi Fructus;
quality evaluation;
seed mass;
removal of shell;
bornyl acetate;
gas chromatography （GC）;
thin layer chromatography （TLC）
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2022;28(15):139-144
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the quality of Amomi Fructus in the market， and to compare the difference between the seed mass and shell， so as to provide a basis for standardizing the usage of Amomi Fructus. MethodThe properties， thin layer identification， moisture， the content of bornyl acetate were determined by the methods in the 2020 edition of Chinese Pharmacopoeia， and the ash and extract content were determined according to the collection method of the 2020 edition of Chinese Pharmacopoeia. ResultAmong the 17 batches of samples， except the content of bornyl acetate in 2 batches of Amomum longiligulare， 2 batches of A. longiligulare and A. villosum mixture was lower than the standard， the quality of other samples all met the standard of the 2020 edition of Chinese Pharmacopoeia， but there were two specifications with shell and without shell. The husk rate， volatile oil， extract and bornyl acetate contents of the seed mass and shell were tested. It was found that the content of volatile oil in three kinds of Amomi Fructus seed mass was 1.8-5.3 times that of the corresponding shell， and the content of bornyl acetate in the seed mass was 8.8-62.1 times that of the corresponding shell， but there was little difference in the extract content. ConclusionBased on the above research， it is considered that the content of bornyl acetate in A. longiligulare contained in the 2020 edition of Chinese Pharmacopoeia remains to be discussed. It is tentatively determined that the total ash content of Amomi Fructus should not be more than 10.0%， and the extract content should not be less than 15.0%. At the same time， it is suggested that when Amomi Fructus is used as medicine， the dosage of Amomi Fructus should be calculated according to the removal rate of 20%-30% of shell， and it should be crushed regardless of whether it is used in shell or not.
