Evaluation of Modified Youguiwan and Governor Meridian Moxibustion in Treatment of Erectile Dysfunction of Renal Yang Deficiency Type and Its Influence on Sex Hormone Level and Penile Hemodynamics
10.13422/j.cnki.syfjx.20221022
- VernacularTitle:加味右归丸联合督脉灸治疗肾阳亏虚型勃起功能障碍的疗效评价及对性激素水平、阴茎血流动力学的影响
- Author:
Liyan GENG
1
;
Zixue SUN
1
;
Pengchao LI
1
;
Xiang CHEN
1
;
Mingyang WU
1
Author Information
1. Henan Province Hospital of Traditional Chinese Medicine， Second Affiliated Hospital of Henan University of Chinese Medicine， Zhengzhou 450002， China
- Publication Type:Journal Article
- Keywords:
erectile dysfunction;
governor meridian moxibustion;
modified Youguiwan;
kidney Yang deficiency
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2022;28(15):8-14
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the clinical effect of governor meridian moxibustion combined with modified Youguiwan in treating erectile dysfunction of kidney Yang deficiency type and its influence on the level of sex hormones and penile hemodynamics. MethodA total of 120 patients were randomized into the control group （60 cases in total， 3 dropouts/lost to follow-ups， 57 finally included） and treatment group （60 cases in total， 2 dropouts/lost to follow-ups， 58 finally included） with the random number table method. Both groups received governor meridian moxibustion （1 time/w， a total of 4 times）. In addition， the control group took oral compound Xuanju capsule （3 capsules/time， 3 times/d）， and the treatment group was given Jiawei Youguiwan （Chinese medicine decoction， 1 dose/d）. The administration lasted 4 weeks for both groups. The scores of 5th edition international index of erectile function （IIEF-5）， erection quality scale （EQS）， and erectile hardness score （EHS）， traditional Chinese medicine （TCM） syndrome score， levels of sex hormones ［testosterone （T）， follicle-stimulating hormone （FSH）， luteinizing hormone （LH）， prolactin （PRL）］， and parameters of penile hemodynamics ［peak systolic velocity （PSV）， end-diastolic volume （EDV）， and resistance index （RI）］ were recorded. ResultAfter treatment， the total effective rate was 87.93% （51/58） in the treatment group， higher than the 71.93% （41/57） in the control group （χ2=4.600 3， P<0.05）. After treatment， compared with before treatment，the treatment group registered increase in the scores of IIEF-5， EQS， and EHS （P<0.01）， decrease in TCM syndrome score （P<0.01）， rise of serum T level （P<0.05）， reduction in the levels of FSH， LH， and PRL （P<0.05）， increase in the levels of PSV and RI （P<0.05）， and down-regulation of EDV level （P<0.05）. ConclusionGovernor meridian moxibustion combined with modified Youguiwan can effectively improve the penile erectile function， erectile hardness， and erection quality， and relieve the clinical symptoms of erectile dysfunction patients of kidney Yang deficiency type.
