Traditional Chinese and Western Medicine in Treatment of Postmenopausal Osteoporosis： A Review
10.13422/j.cnki.syfjx.20220597
- VernacularTitle:中西医治疗绝经后骨质疏松症的研究进展
- Author:
Sheng-hui YI
1
;
Wen-hua ZHAO
2
;
Hui REN
3
;
Peng ZHANG
2
;
Jian-guo LIU
1
;
Wen TANG
1
;
Xiao-bing JIANG
3
Author Information
1. Yueyang Traditional Chinese Medicine Hospital，Yueyang 414000，China
2. Guangzhou University of Chinese Medicine，Guangzhou 510000，China
3. The First Affiliated Hospital of Guangzhou University of Chinese Medicine，Guangzhou 510000，China
- Publication Type:Journal Article
- Keywords:
postmenopausal osteoporosis;
traditional Chinese medicine treatment;
syndrome differentiation and treatment;
western medicine treatment;
research progress
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2022;28(5):274-282
- CountryChina
- Language:Chinese
-
Abstract:
Postmenopausal osteoporosis （PMOP） is a systemic disease characterized by increased bone fragility caused by insufficient estrogen secretion in women after menopause，resulting in decreased bone mass and damage to the microstructure of bone tissues. The main clinical manifestations are low back pain，osteoporotic fractures，spinal deformities，and multiple organ dysfunction. PMOP directly leads to high morbidity， high mortality， and a decline in the quality of life. In addition to miss diagnosis， it is often not treated in time. In recent years， significant progress has been made in the research on factors related to the pathogenesis of PMOP. Based on the previous findings in recent years，this article described three major pathogenesis of PMOP， including intestinal flora imbalance，oxidative stress，and abnormal differentiation of bone marrow mesenchymal stem cells （BMMSCs）， and analyzed the current status of PMOP treatment， such as syndrome differentiation and treatment，acupuncture and moxibustion，exercise therapy， and external treatment in traditional Chinese medicine （TCM）， and basic measures，drug intervention，and physical therapy in western medicine. Among them，drug intervention in western medicine treatment is generally divided into bone resorption inhibitors，bone formation promoters，and other mechanism drugs according to the mechanism of action. This article summarized the specific methods and effects or mechanisms of TCM and western medicine in the clinical treatment of PMOP，which is expected to provide a reference for formulating reasonable health management models and drug treatments in the future.
