Present Situation Analysis and Thinking on Quality Control Mode of Chinese Materia Medica
10.13422/j.cnki.syfjx.20212054
- VernacularTitle:中药质量控制模式的现状分析与思考
- Author:
Shanshan JU
1
;
Yaolei LI
1
;
Zhijian LIN
1
;
Bing ZHANG
1
;
Zhixin REN
1
Author Information
1. School of Chinese Materia Medica，Beijing University of Chinese Medicine，Beijing 102488，China
- Publication Type:Journal Article
- Keywords:
traditional Chinese medicine （TCM）;
quality control;
control extract;
fingerprint;
quality marker （Q-Marker）;
grade evaluation;
integrated quality view
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2022;28(18):269-274
- CountryChina
- Language:Chinese
-
Abstract:
The quality of Chinese materia medica is the premise to ensure its safety and effectiveness in clinical application， and the standardization of Chinese materia medica quality is the most important to realize the sustainable development of traditional Chinese medicine （TCM）. At present， the quality control system of Chinese materia medica has been transformed from a single chemical evaluation to the overall quality control guided by clinical efficacy. However， some quality control items of decoction pieces are still lacking or imperfect in the drug standard of prescription， which makes it difficult to guarantee the effectiveness and safety of Chinese materia medica in clinical application. Based on this， the quality control models and innovative ideas of Chinese materia medica were analyzed and discussed from the perspectives of chemical analysis， biological evaluation and clinical application in this paper. Aiming at the existing problems and actual needs in the control system of Chinese materia medica， this paper proposed the improvement strategies in accordance with the characteristics of TCM， in order to provide theoretical basis for the related research on quality control of Chinese materia medica.
