Research Progress on Relationship Between Intestinal Flora and Osteoporosis and Regulation of Traditional Chinese Medicine： A Review
10.13422/j.cnki.syfjx.20221837
- VernacularTitle:肠道菌群与骨质疏松的关系及中药调节研究进展
- Author:
Jianchun ZHONG
1
;
Xingwen XIE
2
;
Dingpeng LI
2
;
Ning LI
3
;
Haixia SU
3
;
Yunlong GUO
3
Author Information
1. Gansu Provincial Hospital of Traditional Chinese Medicine，Lanzhou 730050，China
2. The Second People's Hospital of Gansu Province，Lanzhou 730030，China
3. Gansu University of Chinese Medicine，Lanzhou 730030，China
- Publication Type:Journal Article
- Keywords:
gut-kidney-bone;
osteoporosis;
intestinal flora;
renal osteopathy
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2022;28(18):237-244
- CountryChina
- Language:Chinese
-
Abstract:
With the gradual aggravation of aging in China， the prevalence of osteoporosis is increasing year by year. Osteoporosis has become a major public health problem threatening the health of middle-aged and elderly people， especially middle-aged and elderly women. There are many predisposing factors and complex pathogenesis of osteoporosis. The interpretation of osteoporosis has been the focus of clinical research in recent years. How to prevent and treat osteoporosis more effectively has also become a major problem faced by researchers. In recent years， the balance and homeostasis of calcium and phosphorus regulated by intestinal absorption， renal excretion and bone have become one of the hot topics， and the balance and homeostasis of calcium and phosphorus in vivo are the key to normal bone homeostasis. At the same time， as a complex microbial community living in the gastrointestinal tract， intestinal flora can produce a variety of regulators affecting metabolism. It has been widely confirmed that it acts on the body indirectly or directly， in multiple ways and targets to prevent and treat osteoporosis. Therefore， further exploring the role and mechanism of intestine kidney bone axis in osteoporosis plays a far-reaching significance for the prevention and treatment of osteoporosis. In recent years， scholars have made a lot of exploration on the prevention and treatment of osteoporosis with traditional Chinese medicine （TCM）， and found that TCM can intervene the expression of intestinal flora and play the effect of prevention and treatment of osteoporosis. Based on the "intestine kidney bone axis"， this paper briefly discusses the integrated traditional Chinese and western medicine of kidney and osteoporosis， intestine and osteoporosis， intestine kidney axis， the treatment of kidney from intestine， intestine and osteoporosis， and the application of TCM in regulating intestinal flora in osteoporosis， in order to provide new ideas for the prevention and treatment of osteoporosis.
