Recent progress in the diagnosis of vitreoretinal lymphoma
10.3980/j.issn.1672-5123.2022.9.10
- VernacularTitle:玻璃体视网膜淋巴瘤的诊断进展
- Author:
Sha TIAN
1
;
Kun CHEN
1
;
Qing-Ping WANG
1
Author Information
1. Department of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China
- Publication Type:Journal Article
- Keywords:
vitreoretinal lymphoma;
diagnosis;
review
- From:
International Eye Science
2022;22(9):1468-1472
- CountryChina
- Language:Chinese
-
Abstract:
Vitreoretinal lymphoma(VRL)is a rare and aggressive non-Hodgkin's lymphoma, and its early and correct diagnosis is still a great challenge because of its non-specific clinical presentation. For VRL diagnosis, pathological cytology is still the gold standard, but its diagnosis needs to combine with clinical manifestations, imaging features, immunological and molecular technology and so on. With the advancement of diagnostic technology, more efficient techniques of cytology and assistant diagnosis have been explored. Cytokines and interleukin score for intraocular lymphoma diagnosis(ISOLD), myeloid differentiation gene 88(MYD88)mutation and next-generation sequencing have higher diagnostic accuracy, so they have gradually become important auxiliary diagnostic methods and research hotspots.
