Four new diphenyl ether derivatives from a mangrove endophytic fungus Epicoccum sorghinum.
10.1016/S1875-5364(22)60171-7
- Author:
Jun-Jie ZHU
1
;
Qi-Sen HUANG
1
;
Sheng-Quan LIU
1
;
Wei-Jia DING
1
;
Ya-Hong XIONG
2
;
Chun-Yuan LI
3
Author Information
1. Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
2. Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China. Electronic address: xiongyahong@scau.edu.cn.
3. Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China. Electronic address: chunyuanli@scau.edu.cn.
- Publication Type:Journal Article
- Keywords:
Antimicrobial activity;
Diphenyl ether;
Epicoccum sorghinum;
Secondary metabolite
- MeSH:
Anti-Bacterial Agents/pharmacology*;
Antifungal Agents/chemistry*;
Ascomycota;
Escherichia coli;
Microbial Sensitivity Tests;
Molecular Structure;
Phenyl Ethers/chemistry*
- From:
Chinese Journal of Natural Medicines (English Ed.)
2022;20(7):537-540
- CountryChina
- Language:English
-
Abstract:
Four new diphenyl ethers, named epicoccethers K-N (1-4), were purified from the fermentation medium of a fungus Epicoccum sorghinum derived from Myoporum bontioides, and identified through HR-ESI-MS and NMR spectral analysis. Except that compound 1 showed moderate antifungal activity against Penicillium italicum and Fusarium graminearum, the other three compounds showed stronger activity against them than triadimefon. All of them showed moderate or weak antibacterial activity towards Staphylococcus aureus and Escherichia coli with O6 and O78 serotypes except that 3 was inactive to E. coli O6.
