Microorganism-derived biological macromolecules for tissue engineering.
10.1007/s11684-021-0903-0
- Author:
Naser AMINI
1
;
Peiman Brouki MILAN
2
;
Vahid Hosseinpour SARMADI
1
;
Bahareh DERAKHSHANMEHR
3
;
Ahmad HIVECHI
1
;
Fateme KHODAEI
4
;
Masoud HAMIDI
5
;
Sara ASHRAF
6
;
Ghazaleh LARIJANI
6
;
Alireza REZAPOUR
7
Author Information
1. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, 1591639675, Iran.
2. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, 1591639675, Iran. brouki.p@iums.ac.ir.
3. Institutes of Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, 1449614535, Iran.
4. Burn Research Center, Department of Plastic and Reconstructive Surgery, Iran University of Medical Sciences, Tehran, 1591639675, Iran.
5. Department of Medical Biotechnology, Faculty of Paramedicine, Guilan University of Medical Sciences, Rasht, 4477166595, Iran.
6. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, 1477893855, Iran.
7. Cellular and Molecular Research Centre, Qom University of Medical Sciences, Qom, 3715835155, Iran. Alireza.Rezapour@yahoo.com.
- Publication Type:Review
- Keywords:
biological macromolecules;
carbohydrate;
exopolysaccharide;
regenerative medicine;
tissue engineering
- MeSH:
Biocompatible Materials/chemistry*;
Humans;
Hyaluronic Acid;
Regenerative Medicine;
Tissue Engineering;
Tissue Scaffolds/chemistry*
- From:
Frontiers of Medicine
2022;16(3):358-377
- CountryChina
- Language:English
-
Abstract:
According to literature, certain microorganism productions mediate biological effects. However, their beneficial characteristics remain unclear. Nowadays, scientists concentrate on obtaining natural materials from live creatures as new sources to produce innovative smart biomaterials for increasing tissue reconstruction in tissue engineering and regenerative medicine. The present review aims to introduce microorganism-derived biological macromolecules, such as pullulan, alginate, dextran, curdlan, and hyaluronic acid, and their available sources for tissue engineering. Growing evidence indicates that these materials can be used as biological material in scaffolds to enhance regeneration in damaged tissues and contribute to cosmetic and dermatological applications. These natural-based materials are attractive in pharmaceutical, regenerative medicine, and biomedical applications. This study provides a detailed overview of natural-based biomaterials, their chemical and physical properties, and new directions for future research and therapeutic applications.
