Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda.
- Author:
Furong GUI
1
;
Tianming LAN
2
;
Yue ZHAO
1
;
Wei GUO
3
;
Yang DONG
1
;
Dongming FANG
2
;
Huan LIU
2
;
Haimeng LI
2
;
Hongli WANG
2
;
Ruoshi HAO
4
;
Xiaofang CHENG
5
;
Yahong LI
6
;
Pengcheng YANG
7
;
Sunil Kumar SAHU
2
;
Yaping CHEN
1
;
Le CHENG
8
;
Shuqi HE
1
;
Ping LIU
5
;
Guangyi FAN
9
;
Haorong LU
10
;
Guohai HU
10
;
Wei DONG
2
;
Bin CHEN
1
;
Yuan JIANG
11
;
Yongwei ZHANG
11
;
Hanhong XU
12
;
Fei LIN
12
;
Bernard SLIPPERS
13
;
Alisa POSTMA
13
;
Matthew JACKSON
13
;
Birhan Addisie ABATE
14
;
Kassahun TESFAYE
14
;
Aschalew Lemma DEMIE
14
;
Meseret Destaw BAYELEYGNE
14
;
Dawit Tesfaye DEGEFU
15
;
Feng CHEN
5
;
Paul K KURIA
16
;
Zachary M KINYUA
16
;
Tong-Xian LIU
17
;
Huanming YANG
18
;
Fangneng HUANG
19
;
Xin LIU
20
;
Jun SHENG
21
;
Le KANG
22
Author Information
- Publication Type:Research Support, Non-U.S. Gov't
- Keywords: Spodoptera frugiperda; chromosome-level genome; cytochrome p450; pesticides; population differentiation
- MeSH: Animals; China; Genomics; Humans; Male; Pesticides; Spodoptera/genetics*; Transcriptome
- From: Protein & Cell 2022;13(7):513-531
- CountryChina
- Language:English
- Abstract: The fall armyworm (FAW), Spodoptera frugiperda, is a destructive pest native to America and has recently become an invasive insect pest in China. Because of its rapid spread and great risks in China, understanding of FAW genetic background and pesticide resistance is urgent and essential to develop effective management strategies. Here, we assembled a chromosome-level genome of a male FAW (SFynMstLFR) and compared re-sequencing results of the populations from America, Africa, and China. Strain identification of 163 individuals collected from America, Africa and China showed that both C and R strains were found in the American populations, while only C strain was found in the Chinese and African populations. Moreover, population genomics analysis showed that populations from Africa and China have close relationship with significantly genetic differentiation from American populations. Taken together, FAWs invaded into China were most likely originated from Africa. Comparative genomics analysis displayed that the cytochrome p450 gene family is extremely expanded to 425 members in FAW, of which 283 genes are specific to FAW. Treatments of Chinese populations with twenty-three pesticides showed the variant patterns of transcriptome profiles, and several detoxification genes such as AOX, UGT and GST specially responded to the pesticides. These findings will be useful in developing effective strategies for management of FAW in China and other invaded areas.