Plant Pharmacophylogeny: Review and Future Directions.
10.1007/s11655-020-3270-9
- Author:
Xue GONG
1
;
Min YANG
1
;
Chun-Nian HE
2
;
Ya-Qiong BI
3
;
Chun-Hong ZHANG
1
;
Min-Hui LI
4
;
Pei-Gen XIAO
5
Author Information
1. Department of Pharmacy, Baotou Medical College, Baotou, Inner Mongolia Autonomous Region, 014040, China.
2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
3. Pharmaceutical Laboratory, Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot, 010020, China.
4. Department of Pharmacy, Baotou Medical College, Baotou, Inner Mongolia Autonomous Region, 014040, China. prof_liminhui@yeah.net.
5. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China. pgxiao@implad.ac.cn.
- Publication Type:Review
- Keywords:
chemical composition;
curative effect;
molecular phylogeny;
pharmacophylogeny;
phytogroup
- MeSH:
Alkaloids;
Glycosides;
Plant Extracts/chemistry*;
Plants, Medicinal/chemistry*;
Saponins;
Terpenes
- From:
Chinese journal of integrative medicine
2022;28(6):567-574
- CountryChina
- Language:English
-
Abstract:
Medicinal plants have provided numerous medicinal active ingredients for thousands of years and these ingredients have been used in Chinese medicine (CM) and traditional pharmacologies worldwide. Recently, the exploitation and utilisation of medicinal plant resources has increased significantly. The results of the studies have led to the identification of many active components, such as steroidal alkaloids, saponins, terpenoids, and glycosides, in various medicinal plants with different evolutionary levels. Moreover, research on the chemical classification, molecular phylogeny, and pharmacological activity of medicinal plants is increasing in popularity. Pharmacophylogeny is an interdisciplinary topic that studies the correlation between plant phylogeny, chemical composition, and curative effects (pharmacological activity and the traditional curative effect) of medicinal plants. In addition, it provides the basic tools to enable research and development of CM resources. This literature review, based on the genetic relationship between phytogroup and species, highlights the formation process, research content, applications, and future directions of pharmacophylogeny.
