The Role of Platelet Exosomes in Atherogenic Thrombosis --Review.
10.19746/j.cnki.issn.1009-2137.2022.03.051
- Author:
Dong-Lian TAO
1
;
Shan DENG
1
;
Yue HU
1
;
Xiu-Quan WU
1
;
Yi-Jian CHEN
2
Author Information
1. Gannan Medical College, The First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China.
2. Department of Hematology, The First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China,E-mail：chenyj2005@163.com.
- Publication Type:Review
- Keywords:
angiogenesis;
atherosclerosis;
endothelial cell dysfunction and apoptosis;
inflammation;
blood coagulation;
platelet-derived exosomes;
thrombosis
- MeSH:
Apoptosis;
Atherosclerosis/pathology*;
Blood Platelets/pathology*;
Exosomes/pathology*;
Humans;
Thrombosis
- From:
Journal of Experimental Hematology
2022;30(3):975-978
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are subtypes of extracellur vesicles containing a variety of cell-specific proteins, lipids and nucleic acids released during cell activation or apoptosis, and play the role of intercellur communication mediators in different physiological and pathological processes. With the development of research in recent years, the role of platelet-derived exosomes in cardiovascular diseases has attracted extensive attention. This paper reviews the role of platelet-derived exosomes in atherosclerotic thrombosis and the potential role of platelet-derived exosomes as biomarkers for the diagnosis and treatment of atherosclerotic thrombotic disease and the problems to be solved.
