The Efficacy of Rh Phenotype Matched Blood Transfusion.
10.19746/j.cnki.issn.1009-2137.2022.03.033
- Author:
Jun-Hui JIA
1
;
Xiao-Yun GAO
1
;
Hua TIAN
1
;
Wei BAI
1
;
Xin-Hua WANG
2
Author Information
1. Department of Blood Transfusion, Aerospace Center Hospital, Beijing 100049, China.
2. Department of Blood Transfusion, Aerospace Center Hospital, Beijing 100049, China,E-mail: wangxinhua721@163.com.
- Publication Type:Journal Article
- Keywords:
Rh phenotype;
efficacy of blood transfusion;
matched blood transfusion
- MeSH:
Bilirubin;
Blood Transfusion;
Erythrocyte Transfusion/adverse effects*;
Hemoglobins/analysis*;
Humans;
Phenotype;
Retrospective Studies
- From:
Journal of Experimental Hematology
2022;30(3):865-869
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze and evaluate the efficacy of Rh phenotype matched blood transfusion.
METHODS:The increasing of hemoglobin (Hb) and hemolysis tests in the patients treated by Rh matched red blood cells or not, as well as the first time unmatched transfusions and the unmatched transfusions happened again after a period (≥10 d) were retrospectively analyzed.
RESULTS:A total of 674 times transfusions in 120 patients were evaluated. The increasing of Hb in each unit was higher in the patients treated by Rh matched blood transfusion (vs unmatched) [(33.397±1.475) g/U vs (29.951±1.304) g/U, P=0.033], while the increasing of Hb at first time unmatched transfusion and the second time unmatched transfusion was not statistically different[ (28.942±2.083) g/U vs (30.686±1.737) g/U, P=0.589]. The level of lactate dehydrogenase were related to erythrocyte washing, irradiation, period of validity and the second time unmatched transtusion (all P<0.05); the levels of total bilirubin (TBil), direct bilirubin (DBil) and indirect bilirubin (IBil) between the first time unmatched transfusion and the second time unmatched transfusion were statistically different (all P<0.05).
CONCLUSION:For the patients need multiple blood transfusions, Rh phenotype matched blood transfusion can reduce the exposure to Rh allogenic antigens, improve the efficacy and ensure the safety of blood transfusion.
