Comparative Analysis of Thromboelastogram and Coagulation Items in Mongolian Patients with Thrombosis.
10.19746/j.cnki.issn.1009-2137.2022.03.031
- Author:
Guo-Li LIU
1
,
2
;
Xiu-Jun SONG
3
;
Ying-Ying MA
4
;
Hua JIN
2
;
Xin-Ru WANG
5
Author Information
1. Graduate Training Base of Jinzhou Medical University (PLA Rocket Army Characteristic Medical Center), Beijing 100088, China
2. Affiliated Hospital of Inner Mongolia Minzu University, Tongliao 028000， Inner Mongolia Autonomous Region, China.
3. Department of Clinical Laboratory, PLA Rocket Army Characteristic Medical Center， Beijing 100088, China,E-mail:songxiujun1979@163.com.
4. Department of Clinical Laboratory, PLA Rocket Army Characteristic Medical Center， Beijing 100088, China.
5. Department of Clinical Laboratory, PLA Rocket Army Characteristic Medical Center， Beijing 100088, China,E-mail: wangxinru@126.com.
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
coagulation test;
thromboelastography;
thrombosis
- MeSH:
Aged;
Blood Coagulation;
Blood Coagulation Tests/methods*;
Cerebral Infarction;
Humans;
Middle Aged;
Retrospective Studies;
Thrombelastography/methods*;
Thrombosis
- From:
Journal of Experimental Hematology
2022;30(3):856-860
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the age distribution of Mongolian patients with cerebral infarction caused by thrombosis and the correlation and consistency between thromboelastography (TEG) and four parameters of coagulation.
METHODS:The age distribution of 298 Mongolian patients with cerebral infarction treated in Affiliated Hospital of Inner Mongolia Minzu University from January 2020 to December 2021 and their TEG, four items of routin coagulation and platelet count were analyzed retrospectively. The correlation and consistency of above-mentioned two detection methods were statistically analyzed.
RESULTS:The onset age of 298 Mongolian patients with cerebral infarction was mainly 61-70 years old, accounting for 38.3%, followed by 51-60 years old, accounting for 26.8%. The R time detected by TEG was linearly correlated with PT and APTT（r=0.186，r=0.152）. K value, MA value and α-Angle measured by TEG was linearly correlated with Fib (r=-0.364，r=0.616，r=0.359), K value, MA value and α-Angle measured by TEG was linearly correlated with Plt (r=0.318，r=0.519，r=0.301). The R time detected by TEG was consistent with PT and APTT, and the Kappa values were 0.252 (P<0.001), 0.336 (P<0.001). K, MA, and α-Angle measured by TEG was consistent with Fib, the Kappa values were 0.265 (P<0.001), 0.289 (P<0.001) and 0.290 (P<0.001), respectively; K、MA and α-Angle measured by TEG was consistent with Plt, the Kappa values were 0.276 (P<0.001), 0.285 (P<0.001) and 0.302 (P<0.001), respectively.
CONCLUSION:The onset age of Mongolian patients with cerebral infarction caused by thrombosis is mainly 61-70 years old, followed by 51-60 years old. The onset age shows a younger trend. There is a significant correlation between TEG and coagulation, but the consistency is weak, therefore, the two methods can not be replaced each other.
