Comparative study on Sichuan yak pericardium and Australian cattle pericardium.
10.7507/1001-5515.202202044
- Author:
Yicong ZUO
1
;
Ke KANG
2
;
Dapeng SHANG
3
;
Xiayan YANG
3
;
Yao WU
4
;
Qifeng YU
3
;
Xiantao WEN
3
Author Information
1. Chengdu NewMed Biotechnology Co., Ltd, Chengdu 611139, P. R. China.
2. Institute of Regulatory Science for Medical Device/College of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China.
3. Shanghai NewMed Medical Co., Ltd, Shanghai 201321, P. R. China.
4. National Engineering Research Center for Biomaterials/College of Biomedical Engineering, Sichuan University, Chengdu 610064, P. R. China.
- Publication Type:Journal Article
- Keywords:
Anti-calcification performance;
Australian cattle pericardium;
Fundamental property;
Sichuan yak pericardium
- MeSH:
Animals;
Australia;
Bioprosthesis;
Cattle;
Heart Valve Prosthesis;
Pericardium
- From:
Journal of Biomedical Engineering
2022;39(3):537-543
- CountryChina
- Language:Chinese
-
Abstract:
Currently, as the key raw material of artificial biological heart valve, bovine pericardium is mainly depend on import and has become a "bottleneck" challenge, greatly limiting the development of domestic biological heart valve. Therefore, the localization of bovine pericardium is extremely urgent. In this study, the pericardium of Sichuan yak was compared with that of Australian cattle in terms of fundamental properties and anti-calcification performance. The results demonstrated that the appearance and thickness of yak pericardium were more advantageous than the Australian one. Sichuan yak pericardium and Australian cattle pericardium had comparable performance in shrinkage temperature, mechanical test and anti-calcification test. This study preliminarily verifies the feasibility of substitution of Australian cattle pericardium by Sichuan yak pericardium and promotes the progression of bovine pericardium localization with data support.
