White blood segmentation based on dual path and atrous spatial pyramid pooling.
10.7507/1001-5515.202107043
- Author:
Zuoyong LI
1
;
Yan LU
2
;
Xinrong CAO
1
;
Lida QIU
3
;
Xuejun QIN
4
Author Information
1. College of Computer and Control Engineering, Minjiang University, Fuzhou 350121, P. R. China.
2. Fujian Provincial Key Laboratory of Information Processing and Intelligent Control (Minjiang University), Fuzhou 350121, P. R. China.
3. College of Physics and Electronic Information Engineering, Minjiang University, Fuzhou 350121, P. R. China.
4. Department of Clinical Laboratory, The People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou 350001, P. R. China.
- Publication Type:Journal Article
- Keywords:
Atrous spatial pyramid pooling;
Convolutional neural network;
Dual path network;
Image segmentation;
White blood cell segmentation
- MeSH:
Algorithms;
Leukocytes
- From:
Journal of Biomedical Engineering
2022;39(3):471-479
- CountryChina
- Language:Chinese
-
Abstract:
The count and recognition of white blood cells in blood smear images play an important role in the diagnosis of blood diseases including leukemia. Traditional manual test results are easily disturbed by many factors. It is necessary to develop an automatic leukocyte analysis system to provide doctors with auxiliary diagnosis, and blood leukocyte segmentation is the basis of automatic analysis. In this paper, we improved the U-Net model and proposed a segmentation algorithm of leukocyte image based on dual path and atrous spatial pyramid pooling. Firstly, the dual path network was introduced into the feature encoder to extract multi-scale leukocyte features, and the atrous spatial pyramid pooling was used to enhance the feature extraction ability of the network. Then the feature decoder composed of convolution and deconvolution was used to restore the segmented target to the original image size to realize the pixel level segmentation of blood leukocytes. Finally, qualitative and quantitative experiments were carried out on three leukocyte data sets to verify the effectiveness of the algorithm. The results showed that compared with other representative algorithms, the proposed blood leukocyte segmentation algorithm had better segmentation results, and the mIoU value could reach more than 0.97. It is hoped that the method could be conducive to the automatic auxiliary diagnosis of blood diseases in the future.
