Brachial-Ankle Pulse Wave Velocity as a Screen for Arterial Stiffness: A Comparison with Cardiac Magnetic Resonance.
10.3349/ymj.2015.56.3.617
- Author:
Eun Kyoung KIM
1
;
Sung A CHANG
;
Shin Yi JANG
;
Ki Hong CHOI
;
Eun Hee HUH
;
Jung Hyun KIM
;
Sung Mok KIM
;
Yeon Hyeon CHOE
;
Duk Kyung KIM
Author Information
1. Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dkkim@skku.edu
- Publication Type:Original Article ; Comparative Study ; Research Support, Non-U.S. Gov't
- Keywords:
Arterial stiffness;
pulse wave velocity;
distensibility;
brachial artery;
magnetic resonance imaging
- MeSH:
Adult;
Ankle Brachial Index/*methods;
Ankle Joint;
Aorta/anatomy & histology/*physiology;
*Blood Flow Velocity;
Cardiovascular Diseases;
Female;
Heart/physiopathology;
Humans;
*Magnetic Resonance Imaging, Cine;
Male;
Pulse Wave Analysis/*methods;
Regional Blood Flow;
Reproducibility of Results;
Risk Factors;
*Vascular Stiffness
- From:Yonsei Medical Journal
2015;56(3):617-624
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Despite technical simplicity and the low cost of brachial-ankle pulse wave velocity (BA-PWV), its use has been hampered by a lack of data supporting its usefulness and reliability. The aim of this study was to evaluate the usefulness of BA-PWV to measure aortic stiffness in comparison to using cardiovascular magnetic resonance (CMR). MATERIALS AND METHODS: A total of 124 participants without cardiovascular risk factors volunteered for this study. BA-PWV was measured using a vascular testing device. On the same day, using CMR, cross-sectional areas for distensibility and average blood flow were measured at four aortic levels: the ascending, upper thoracic descending, lower thoracic descending, and abdominal aorta. RESULTS: Compared to PWV measured by CMR, BA-PWV values were significantly higher and the differences therein were similar in all age groups (all p<0.001). There was a significant correlation between BA-PWV and PWV by CMR (r=0.697, p<0.001). Both BA-PWV and PWV by CMR were significantly and positively associated with age (r=0.652 and 0.724, p<0.001). The reciprocal of aortic distensibility also demonstrated a statistically significant positive correlation with BA-PWV (r=0.583 to 0.673, all p<0.001). CONCLUSION: BA-PWV was well correlated with central aortic PWV and distensibility, as measured by CMR, regardless of age and sex.
