Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

Author: Mulyadi TANJUNG ¹ ; Tjitjik Srie TJAHJANDARIE ; Shola MARDHIYYAH ; Ghinsha Zakatina RAHMAN ; Muhammad Fajar ALDIN ; Ratih Dewi SAPUTRI ; Norizan AHMAT
Author Information

1. Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia
Publication Type:Original Article
From:Natural Product Sciences 2022;28(2):58-61
CountryRepublic of Korea
Language:English
Abstract: Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1 - 2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1 - 3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC 50 value of 11.2 µM.