A Case of Burkitt's Lymphoma with Bilateral Renal Enlargement.
- Author:
Jun Hee PARK
1
;
In Kyu LEE
;
Jong Woon CHOI
;
Soon Ki KIM
;
Byong Kwan SON
;
Jin Ju KIM
Author Information
1. Department of Pediatrics, College of Medicine, In Ha University, Seongnam, Korea.
- Publication Type:Original Article
- Keywords:
Burkitt's lymphoma;
Bilateral renal enlargement
- MeSH:
Allopurinol;
B-Lymphocytes;
Burkitt Lymphoma*;
Cerebrospinal Fluid;
Drug Therapy, Combination;
Edema;
Flow Cytometry;
Humans;
Lymphoma;
Male;
Radiotherapy;
Tumor Lysis Syndrome;
Ultrasonography
- From:Journal of the Korean Pediatric Society
1995;38(1):122-128
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Burkitt's lymphoma is a distinct pathologic entity characterized as a diffuse undifferentiated malignant lymphoma of B-lymphocyte origin. We experienced a case of Burkitt's lymphoma with bilateral renal enlargement in which a 3year-old male patient was admitted with complaints of abdominal distention and facial edema. Laboratory examination revealed positivity for CD 19, CD 10, CD 20 and c-myc on flow cytometry, bilateral renal enlargement(10x12cm in longitudinal length) on abdominal ultrasonogram and CT, malignant lymphoma of Buritt's type with prominent nucleoli and cytospin of cerebrospinal fluid. Initially he showed tumor lysis syndrome and clinical stage D by Zigler(stage IV by Murphy) with CNS involvement. After initial management with hydration, urine alkalinization and allopurinol, combination chemotherapy had been applied with the craniospinal radiotherapy according to the CCG 503 II regimane, with achievement of complete remission. Thus we report a case of Burkitt's lymphoma with bilateral renal enlargement with a biref review of literatures.
