A Case of Elastosis Perforans Serpiginosa in a Patient with Down Syndrome
- Author:
Hyung Don KOOK,
1
;
Narang HONG
;
Dong Heon LEE
;
Hye Jung JUNG
;
Jiyoung AHN
;
Mi Youn PARK
Author Information
1. Department of Dermatology, National Medical Center, Seoul, Korea
- Publication Type:Case Report
- From:Korean Journal of Dermatology
2022;60(6):387-389
- CountryRepublic of Korea
- Language:English
-
Abstract:
Elastosis perforans serpiginosa (EPS) is a rare condition that belongs to the group of acquired perforating dermatosis. It usually appears as keratotic papules in serpiginous configuration with central atrophy on the head, nape, and extremities. It is characterized by the transepidermal elimination of elastic fibers with clumping and vertical orientation of elastic fibers. In many cases, it is associated with genetic or connective tissue diseases. A 26-year-old female patient with Down syndrome presented with brownish keratotic papules on both arms. The lesion had been present for 2 years, but there were no symptoms. The biopsy specimen showed transepidermal elimination of the degenerated elastic fibers. Verhoeff elastic staining revealed an increased number of thick elastic fibers. Based on these findings, the patient was diagnosed with EPS. Treatment with CO 2 laser was performed with a successful outcome.
