Risk of Subsequent Events in Patients With Minor Ischemic Stroke or HighRisk Transient Ischemic Attack
- Author:
Keon-Joo LEE
1
;
Dong Woo SHIN
;
Hong-Kyun PARK
;
Beom Joon KIM
;
Jong-Moo PARK
;
Kyusik KANG
;
Tai Hwan PARK
;
Kyung Bok LEE
;
Keun-Sik HONG
;
Yong-Jin CHO
;
Dong-Eog KIM
;
Wi-Sun RYU
;
Byung-Chul LEE
;
Kyung-Ho YU
;
Mi-Sun OH
;
Soo Joo LEE
;
Jae Guk KIM
;
Jun LEE
;
Jae-Kwan CHA
;
Dae-Hyun KIM
;
Joon-Tae KIM
;
Kang-Ho CHOI
;
Jay Chol CHOI
;
Eva LESÉN
;
Jonatan HEDBERG
;
Amarjeet TANK
;
Edmond G. FITA
;
Ji Eun SONG
;
Ji Sung LEE
;
Juneyoung LEE
;
Hee-Joon BAE
;
Author Information
- Publication Type:Brief Communication
- From:Journal of Korean Medical Science 2022;37(33):e254-
- CountryRepublic of Korea
- Language:English
- Abstract: This study aimed to present the prognosis after minor acute ischemic stroke (AIS) or transient ischemic attack (TIA), using a definition of subsequent stroke in accordance with recent clinical trials. In total, 9,506 patients with minor AIS (National Institutes of Health Stroke Scale ≤ 5) or high-risk TIA (acute lesions or ≥ 50% cerebral artery steno-occlusion) admitted between November 2010 and October 2013 were included. The primary outcome was the composite of stroke (progression of initial event or a subsequent event) and all-cause mortality. The cumulative incidence of stroke or death was 11.2% at 1 month, 13.3% at 3 months and 16.7% at 1 year. Incidence rate of stroke or death in the first month was 12.5 per 100 person-months: highest in patients with large artery atherosclerosis (17.0). The risk of subsequent events shortly after a minor AIS or high-risk TIA was substantial, particularly in patients with large artery atherosclerosis.