Preventive effect of dentifrice containing 1,450 ppm fluoride and sodium pyrophosphate
10.11149/jkaoh.2022.46.2.63
- Author:
Min-Ji PARK
1
;
Ja-Won CHO
;
Hyun-Jun YOO
;
Mi-Hae YUN
;
Kyong-Hoon SHIN
;
Young-Hoon PARK
Author Information
1. Department of Oral Health, Graduate School of Health and Welfare, Dankook University, Cheonan, Korea
- Publication Type:Original Article
- From:Journal of Korean Academy of Oral Health
2022;46(2):63-69
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objectives:This study aimed to evaluate the effects of a toothpaste containing sodium pyrophosphate and a high concentration (1,450 ppm) of fluoride on dental plaque, gingivitis index, and calculus index in a clinical trial.
Methods:This study used an eight-week, randomized, double-blinded, controlled, comparative, parallel design. The participants, who voluntarily signed a consent form, were screened through visit evaluation if they met the selection/exclusion criteria. After a one-week run-in period, the selected participants were randomly assigned to either an experimental or control group in the order of their enrollment. Subsequently, the participants were asked to brush their teeth with the study toothpaste using the rolling method for 3 min, thrice daily, for 8 weeks. Oral examinations were performed at baseline and after 3 weeks, 4 weeks, and 8 weeks. Evaluation of papillary marginal attachment index (PMA index), Talbott’s gingival index, patient hygiene performance index (PHP index), Turesky plaque index, and calculus index were performed during the oral examination.
Results:After 8 weeks, the PMA indices were 7.12 for the control group and 5.00 for experimental groups. In addition, the PHP index was 2.06 for the control group and 1.66 for the experimental group. Significant differences were observed between the control and experimental groups in all indice (P<0.05).
Conclusions:This study shows that using a toothpaste containing sodium fluoride, sodium pyrophosphate, tocopherol acetate, and dental-type silica improves dental plaque removal, reduces gingivitis, and inhibits calculus formation.
