Clear cell sarcoma of the kidney: a case report.
10.3346/jkms.1989.4.3.149
- Author:
Joong Seok SEO
1
;
Yong Wook PARK
;
Kye Yong SONG
;
Seon Taek CHANG
Author Information
1. Department of Pathology, College of Medicine, Chung-Ang University, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Clear cell sarcoma of the kidney;
Wilms' tumor
- MeSH:
Child, Preschool;
Humans;
Immunohistochemistry;
Kidney Neoplasms/metabolism/*pathology;
Male;
Neoplasm Metastasis;
Sarcoma/metabolism/*pathology
- From:Journal of Korean Medical Science
1989;4(3):149-153
- CountryRepublic of Korea
- Language:English
-
Abstract:
Clear cell sarcoma of the kidney (CCSK) is a highly malignant childhood tumor, distinguished from classic Wilms' tumor by its propensity to metastasize to the skeletal system. Authors described a case of CCSK from a 3-year-old boy in the right kidney, showing various histologic features, such as classic, epithelioid, trabecular, neurilemmoma-like, cystic and entrapped collecting tubular pattern. Ultrastructurally epithelial differentiation was absent. Immunohistochemically, none of the intrinsic tumor cells showed positive staining with the antibodies against the keratin, S-100 protein, carcinoembryonic antigen, vimentin, desmin and myoglobin, suggesting primitive mesenchymal cell in origin.
