Funagating Malipant Melanoma after Rupture of the Globe.
- Author:
Sueng Han HAN
1
;
Hong Bok KIM
Author Information
1. Department of Ophthalmology, College of Medicine, Yonsei University, Seoul, Korea.
- Publication Type:Case Report
- MeSH:
Adult;
African Continental Ancestry Group;
Ambulatory Care Facilities;
Anesthesia, General;
Epithelioid Cells;
Humans;
Incidence;
Male;
Melanoma*;
Orbit;
Rare Diseases;
Rupture*;
Sclera
- From:Journal of the Korean Ophthalmological Society
1986;27(5):955-959
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Malignant melanoma is a rare disease. On the average it occurs in from 0.02 to 0.06 of all eye-patients, that is, from 2 to 6 per 10,000. Malignant melanoma is rare among Negroes; the ratio of Caucasian to non-caucasian patients is 250: 1(Hogan and Zimmerman). The sex incidence shows a slight excess of males. Bilater al cases are exceptional. Hereditary influences are little in evidence. The very early stages of a neoplasm are difficult to come upon, but early growths have been found accidentally in eyes enucleated for other reasons. Extraocular entension may take place at a very early stage in the evolution of a malignant melanoma(when it was 2 X 3mm, Schultz-Zehden, 1905), but occurs most readily from the diffuse type of flat or ring-shaped growth. This does not usually occur directly through the sclera which forms a relatively efficient barrier unless the tumor becomes necrotic and the sclera participates in this process. As a general rule extraocular extension takes the path of least resistance along the channels made by the perforating vessels and nerves. A 42 year old Korean man was seen in our outpatient clinic complaining of a dark rapidly growing mass without pain OD for one month period. He was told that he may have intraocular tumor OD of unknown etiology by some ophthalmologist about 3 years ago. But since then he has never consulted with eyespecialist. Right eyeball including large mass was removed under general anesthesia and reported histopathologically to be malignant melanoma of epithelioid cell type. After surgery he received radiation therapy. Total 4,500 rad x-ray irradiation was applied on the right orbital area for 4 weeks.
