Clinical and Microbiological Risk Factors for Community-Associated Clostridioides difficile Infections
- Author:
Young Ah KIM
1
;
Heejung KIM
;
Dokyun KIM
;
Changseung LIU
;
Seok Hoon JEONG
Author Information
- Publication Type:Original Article
- From:Annals of Clinical Microbiology 2022;25(2):53-58
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:The incidence of community-associated (CA) Clostridioides difficile infection (CDI) has increased in Korea. In this study, we evaluated CA-CDI risk factors in terms of clinical features and ribotype considering its region-specific molecular epidemiology.
Methods:A retrospective case-control study was performed on two groups of CDI patients:127 subjects with CA-CDI and 265 subjects with healthcare-associated (HA)-CDI. Risk factors for CA-CDI were evaluated in terms of clinical and microbiological features such as toxin type and ribotype.
Results:A comparison of the two groups of CDI patients revealed that inflammatory bowel disease, diarrhea, abdominal pain, and fever were more closely associated with CA-CDI. The toxin types and ribotypes of C. difficile were similar between the two groups. After adjusting for variables, no risk factors were identified for CA-CDI compared with HA-CDI.
Conclusion:Specific risk factors for CA-CDI were not identified in this study.
