Advance of Application of Taxol in Microtubule Skeleton Function of Nerve Cells after Spinal Cord Injury (review)
10.3969/j.issn.1006-9771.2015.04.004
- VernacularTitle:紫衫醇对脊髓损伤后神经细胞骨架微管作用研究进展
- Author:
Yuming WANG
;
Li TANG
;
Degang YANG
;
Huadong YANG
- Publication Type:Journal Article
- Keywords:
taxol, spinal cord injury, microtubule, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2015;21(4):387-390
- CountryChina
- Language:Chinese
-
Abstract:
The drugs promoting axon regeneration after spinal cord injury has been receiving high attention. Growth, extending and branching of neuron axon is a biological process mediated by cytoskeleton, and microtubule plays an important role on axon structure adjustment and growth. Taxol can reasonably stabilize microtubules, eliminate the obstacles of axon regeneration, and effect on axonal regeneration repair after spinal cord injury. Taxol is mainly used for anti-tumor therapy. This paper reviewed the researches on taxel and neuronal cytoskeletal microtubule.
