Role of Mitogen-activated Protein Kinases Signaling Pathway in Development of Osteoarthritis (review)
10.3969/j.issn.1006-9771.2015.03.012
- VernacularTitle:丝裂原活化蛋白激酶信号通路在骨关节炎发生中作用机制的研究进展
- Author:
Shengcun LI
;
Guoxiang WANG
- Publication Type:Journal Article
- Keywords:
mitogen-activated protein kinases, osteoarthritis, stress, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2015;21(3):292-295
- CountryChina
- Language:Chinese
-
Abstract:
Osteoarthritis (OA) is a common disease among elders and athletes. Mitogen-activated protein kinases (MAPKs) are molecules of stress sensitivity which play a significant role in the occurrence and development of OA. MAPKs are closely related with chondrocyte apoptosis and cartilage degradation. This paper reviewed the related studies between OA and MAPKs.
