The Results of Postoperative Radiotherapy for Early Stage Endometrial Carcinoma.
- Author:
Min Kyu KANG
1
;
Seung Jae HUH
;
Won PARK
;
Jeong Won LEE
;
Byoung Gie KIM
;
Duk Soo BAE
;
Je Ho LEE
;
Ki Heon LEE
;
Kyung Taek LIM
;
Tae Jin KIM
;
Seok Ju SEONG
;
Chong Taik PARK
;
Jeong Eun LEE
;
Young Je PARK
;
Heerim NAM
;
Dongryul OH
;
Do Hoon LIM
;
Yong Chan AHN
Author Information
1. Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sj5201.huh@samsung.com
- Publication Type:Original Article
- Keywords:
Endometrial carcinoma;
Surgery;
Postoperative radiotherapy
- MeSH:
Brachytherapy;
Disease-Free Survival;
Endometrial Neoplasms*;
Female;
Follow-Up Studies;
Humans;
Lymph Node Excision;
Neoplasm Metastasis;
Radiotherapy*;
Recurrence;
Risk Factors
- From:The Journal of the Korean Society for Therapeutic Radiology and Oncology
2006;24(2):116-122
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To determine treatment policy for early stage endometrial carcinoma, we analyzed the results of postoperative radiotherapy. MATERIALS AND METHODS: From Oct. 1994 to Aug. 2002, 42 patients with FIGO stage I endometrial carcinoma received postoperative radiotherapy. All patients received curative surgery and pelvic lymph node dissection was done in 26 patients. Based on the FIGO staging system, 3 were at stage IA, 21 were at stage IB and 18 were at stage IC. Histologically, there were 14 grade 1, 16 grade 2, and 12 grade 3. Nineteen patients received intracavitary brachytherapy and 23 patients did whole pelvic radiotherapy. The median period of follow-up was 41 months (22 to 100 months). RESULTS: Five-year overall survival, disease-free survival, local control, and regional control rates of all patients were 86.0%, 87.9%, 100%, and 97.5%, respectively. All failures were distant metastases in 5 patients and two patients had simultaneous regional recurrences. There was no intrapelvic failure in patients who received intracavitary radiotherapy. Grade 3 chronic complications were found in 1 patient (4.3%), who received whole pelvic radiotherapy. CONCLUSION: We achieved high rates of loco-regional control and survival by curative surgery and postoperative radiotherapy. However, we need to select the type of radiotherapy based on the risk factors for recurrence to reduce the treatment-related complication.
