Default Mode Network Altered in Chronic Pain Caused by Cervical Spondylosis
10.3969/j.issn.1006-9771.2015.01.018
- VernacularTitle:颈椎病慢性疼痛患者的默认网络研究
- Author:
Hua ZHANG
;
Hao WANG
;
Duoduo LI
;
Baolin JIA
;
Zhongjian TAN
;
Hong CHEN
- Publication Type:Journal Article
- Keywords:
: cervical spondylosis;
chronic pain;
default mode network;
support vector machine;
independent component analysis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2015;(1):69-73
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of resting state default mode network (DMN) in patients with chronic pain caused by cervical spondylosis (CPCS). Methods 8 healthy controls and 10 patients accepted functional MRI scanning. Surface based DMN was extracted with independent component analysis (ICA). The functional connectivity of the components of DMN were discriminated with support vector machine (SVM) algorithm from the patients to the controls. Results The DMN connectivity was different in the patients from the controls in some of the component areas. Conclusion DMN of CPCS patients is disorder in multiple brain areas, which may be involved with dysfunction of perception processing, emotion and memory.
