Research progress on the effective components of traditional Chinese medicine for improving AD-related cognitive impairment
10.16438/j.0513-4870.2021-1599
- VernacularTitle:中药有效成分对AD相关认知功能的改善作用及其机制研究进展
- Author:
Meng-yao LEI
;
Pei-pei GAO
;
Jian-gang LONG
- Publication Type:Research Article
- Keywords:
Alzheimer's disease;
traditional Chinese medicine;
senility;
cognitive function;
neuro
- From:
Acta Pharmaceutica Sinica
2022;57(7):1925-1936
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease (AD) and other aging-related diseases have become an important public health issue in China. However, current clinical drugs have failed to reverse the pathological process of AD. The holistic approach of traditional Chinese medicine offers advantages in improving cognitive function in AD through multiple molecular pathways, and may have potential for preventing AD. This paper summarizes the effects of classical traditional Chinese medicine and its active components in the improvement of AD-related cognitive dysfunction and describes the functional targets and related molecular mechanisms. This may have significance for the prevention and treatment of AD through multi-target intervention.