Clinical comprehensive evaluation for Chinese patent medicine based on evidence-based medicine and pharma- coeconomic model
- VernacularTitle:基于循证医学证据和药物经济学模型的中成药临床综合评价
- Author:
Xianshuai TANG
1
;
Lei ZHENG
1
;
Mingzhu ZHANG
1
,
2
;
Yuyao GUAN
1
;
Jing YANG
1
Author Information
1. Dept. of Pharmacy，Shandong Provincial Third Hospital，Jinan 250031，China
2. Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy，Xuzhou Medical Universi ty，Jiangsu Xuzhou 221004，China
- Publication Type:Journal Article
- Keywords:
clinical comprehensive evaluation of drugs;
Chinese patent medicine;
promoting blood circulation and removing
- From:
China Pharmacy
2022;33(15):1870-1875
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To conduct a c omprehensive clinical evaluation method of Chinese patent medicine ，and to provide reference for rational clinical drug use. METHODS Taking the top 10 Chinese patent medicine injections for promoting blood circulation and removing stasis in Shandong province from 2016 to 2020 collected by the National Rational Drug Use Monitoring Network as an example ，the method combining health technology assessment with objective judgement analysis is used to construct the comprehensive evaluation index system ；based on evidence-based medical evidence and pharmacoeconomic model ，the safety ， effectiveness and economy of the drug were evaluated comprehensively ，and the scores were quantified. RESULTS & CONCLUSIONS The final scores of the 10 kinds of Chinese patent medicine injections were between 26 and 37 scores. Safflower yellow for injection scored the highest score in the treatment of cerebral infarction and angina pectoris of coronary heart disease ， while Ginkgo diterpene lactone meglumine injection and Shuxuening injection had the highest scores in the treatment of coronary heart disease. The clinical comprehensive evaluation method of Chinese patent medicine based on evidence-based medical evidence and pharmacoeconomic model can clarify the comprehensive value of Chinese patent medicine in clinic ，promote rational drug use in clinic ，and provide basis for the next adjustment of medical insurance catalogue and essential medicine catalogue ，decision-making of centralized procurement of related drugs.
