Seroprevalence of anti-Streptococcus pneumoniae antibody in the elderly attending physical examination in a district of Shanghai
10.19428/j.cnki.sjpm.2022.21595
- VernacularTitle:上海市某区老年人肺炎链球菌IgG抗体水平分析
- Author:
Weihui BEI
1
;
Tianhan SHEN
2
;
Mingyi CAI
1
;
Qi SHEN
1
;
Hong HU
1
;
Cuiwei XU
1
;
Bing SHEN
1
Author Information
1. Jing’an District Center for Disease Control and Prevention, Shanghai 200072, China
2. Jing’an Temple Community Health Care Center, Shanghai 200041, China
- Publication Type:Journal Article
- Keywords:
elderly;
Streptococcus pneumoniae;
antibody
- From:
Shanghai Journal of Preventive Medicine
2022;34(6):583-586
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo determine the seroprevalence of anti-Streptococcus pneumoniae immunoglobulin G （IgG） antibody and its risk factors in the elderly attending physical examination. MethodsTwo communities were randomly selected， in which the elderly aged over 60 years attending physical examination in the community health care centers were included in the study. A questionnaire survey was conducted， companied by examination for serum anti-Streptococcus pneumoniae IgG antibody. In addition， data of physical examination was collected. Chi-square test and multivariate logistic regression were utilized to determine the risk factors associated with seroprevalence of anti-Streptococcus pneumoniae antibody. ResultsA total of 635 participants were included. The average age was （73.2±7.4） years old. Forty-nine （7.72%） participants tested positive for anti-Streptococcus pneumoniae IgG antibody. The seroprevalence differed by gender （6.49% in male and 8.86% in female）， smoking （5.48% in smokers and 8.01% in non-smokers）， history of pneumonia （7.89% in those suffered from pneumonia in the past year and 7.71% in those didn’t have pneumonia）， history of common cold （10.38% in those had common cold in the past year and 5.87% in those didn’t have cold）， obesity （15.62% in those with obesity and 6.83% in those without obesity）. Further multivariate logistic regression showed the seroprevalence of anti-Streptococcus pneumoniae IgG significantly increased in the elderly with history of common cold （OR： 2.24； 95%CI： 1.21‒4.14）and obesity （OR： 2.81； 95%CI： 1.26‒6.26）. ConclusionSeroprevalence of anti-Streptococcus pneumoniae IgG antibody is low in the elderly attending physical examination. It warrants improving the vaccination of pneumococcal polysaccharide vaccine for the elderly with obesity and susceptibility to common cold.
