Clinical characteristics and risk factors of mycoplasma pneumonia complicated with myocardial damage in children in Qinghai area
10.3969/j.issn.1006-2483.2022.04.035
- VernacularTitle:青海地区小儿支原体肺炎并发心肌受损的临床特征及危险因素
- Author:
Wenhai WANG
1
,
2
;
Ruhai MA
1
,
2
;
Youcang WAN
1
,
2
Author Information
1. Department of Pediatric Critical Medicine, Qinghai Women's and Children'
2. s Hospital , Xining , Qinghai 810000 , China
- Publication Type:Journal Article
- Keywords:
Mycoplasma pneumonia in children;
Myocardial damage;
Clinical features;
Risk factor
- From:
Journal of Public Health and Preventive Medicine
2022;33(4):148-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics and risk factors of myocardial damage in children with mycoplasma pneumonia in Qinghai area, and to provide evidence for clinical diagnosis and treatment. Methods A total of 328 children diagnosed with mycoplasma pneumonia in Qinghai region from June 2016 to June 2020 were selected as the research subjects. According to whether they were complicated with myocardial damage, they were divided into the control group (no myocardial damage, n=185) and the experimental group (complicated with myocardial damage, n=143). The data of the children were collected by using a questionnaire made by our hospital. These included gender, age, fever duration, initiation time of macrocyclic esters and fever degree, etc., and the levels of CK-MB, CK, CTNNI, NT-proBNP, CRP, LDH and RDW were determined. RESULTS: There were no significant differences in age, gender and complications between the two groups (P>0.05). There were statistically significant differences in the use time, fever duration and fever degree between the two groups (P<0.05). In terms of laboratory indicators, there were statistically significant differences in the levels of CK-MB, CK, cTNnI, NT-probNP, CRP, LDH and RDW between the two groups (P<0.05).Logistic regression analysis showed that the duration of fever (OR=3.105), the start time of macrolides (OR=1.457), the degree of fever (OR=2.495), CRP(OR=1.853) and RDW(OR=1.358) were the risk factors for myocardial damage in children with mycoplasma pneumonia in Qinghai area (P<0.05). Conclusion The duration of fever, the initiation time of macrolide drugs, the degree of fever, CRP and RDW are independent risk factors for myocardial damage in children with mycoplasma pneumonia in Qinghai area. The early use of macrolide drugs can prevent myocardial damage, improve the treatment effect and improve the prognosis of children.