Research advances on application of botulinum toxin type A in scar prevention and treatment.
10.3760/cma.j.cn501120-20210208-00054
- Author:
Zhen YU
1
;
Pan REN
2
;
Han ZHANG
1
;
Hui CHEN
1
;
Fu Xin MA
2
Author Information
1. The Plastic and Reconstructive Surgery Department of Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710004, China.
2. Department of Burns and Plastic Surgery, the Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China.
- Publication Type:Review
- MeSH:
Botulinum Toxins, Type A/therapeutic use*;
Cicatrix/prevention & control*;
Extracellular Matrix/pathology*;
Fibroblasts/drug effects*;
Humans;
Wound Healing/drug effects*
- From:
Chinese Journal of Burns
2022;38(4):385-388
- CountryChina
- Language:Chinese
-
Abstract:
The wound healing time, tension of wound edge, proliferation of fibroblast, and extracellular matrix deposition are the important factors of scar formation, and botulinum toxin type A can regulate the above. Prevention and treatment of scar with botulinum toxin type A is one of the hot topics of clinical research in recent years. This paper briefly reviews researches by scholars at home and abroad on the mechanism, clinical application, complications, and adverse effects of botulinum toxin type A in scar prevention and treatment.
