Connective tissue diseases and the liver injury.

VernacularTitle:结缔组织病与肝损伤
Author: Wei Jia DUAN ^{1
,

2} ; Shu Xiang LI ^{1
,

2} ; Ting Ting LYU ^{1
,

2} ; Sha CHEN ^{1
,

2} ; Li Juan FENG ^{1
,

2} ; Xiao Ming WANG ^{1
,

2} ; Xiao Juan OU ^{1
,

2} ; Ji Dong JIA ^{1
,

2}
Author Information

1. Liver Research Center, Beijing Friendship Hospital, Capital Medical University
2. Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis & National Clinical Research Center for Digestive Diseases, Beijing 100050, China.
Publication Type:Journal Article
MeSH: Autoantibodies; Autoimmune Diseases/diagnosis*; Connective Tissue Diseases/diagnosis*; Diagnosis, Differential; Humans; Liver
From: Chinese Journal of Hepatology 2022;30(4):357-361
CountryChina
Language:Chinese
Abstract: Connective tissue disease (CTD) are closely related to liver abnormality. CTD can affect the liver causing various degrees of liver injury, coexist with other liver diseases, especially autoimmune liver disease (ALD). Medications for CTD can also lead to liver injury or reactivate the hepatitis B virus. CTD patients can also be positive for ALD-related autoantibodies without corresponding manifestation; and vis versa. The diagnosis and differential diagnosis should be made on integrating clinical presentation, laboratory, imaging, and histological studies, not solely relying on autoantibody positivity.